"I'm here today because of Stacey Abrams", Winfrey said.
She praised Abrams as a leader who "will serve the underserved of the state of Georgia".
"We have this incredible opportunity to make history", Winfrey told the capacity crowd "We have our inalienable right to vote because the one place where we are all equal, is at the polls".
"I'm here today because Stacey Abrams cares about the things that matter".
"I think what you are seeing here now is Democrats - especially in so many of these suburban House districts where Trump carried it, or it was close - are saying, 'We are counting on those white suburban women this time, especially in the aftermath of all the trouble we have seen with the violence, to say we want a check on Trump, ' " he said.
Winfrey also said she invited herself to campaign for Abrams, and had not been brought in by anybody but herself. "You are disrespecting and disregarding their legacy, their suffering and their dreams, when you don't vote".
Perhaps even more than President Barack Obama, who will campaign for Abrams on Friday, Winfrey's appeal closely aligns with Abrams' political pitch.
Claiming that Abrams is "bankrolled by Hollywood liberals", he blasted Oprah Winfrey's appearance with the Democrat at a pair of town halls in metro Atlanta, as well as actor Will Ferrell's recent campaign appearance in Georgia. For both parties, the result of Georgia governor's race will be an indication of where this big, increasingly purple state goes in the coming years. "I'm kind of a big deal too and I've got a message, I've got a message for all of Stacey Abrams' liberal Hollywood friends. I am here because I want you to remind others of the power".
"I'm canvassing for Stacey Abrams", Winfrey says to a shocked Georgia resident who opened her front door to find the media mogul on her doorstep holding a clipboard.
"Surprised?" the woman, named Denise, said.