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If ISIS's claims on the Tajikistan incident are confirmed, it would the first time Americans have been killed in a terrorist attack outside of the US since August 2017 in Barcelona, according to ABC. One of them also had a stab wound.

A view of a bridge to Afghanistan across Panj river in Panji Poyon border outpost, south of Dushanbe, Tajikistan, May 2008.

New footage has emerged that appears to show four western cyclists killed in Tajikistan were the victims of a deliberate attack that began with them being forced off the road and ended in an assault with knives and guns.

The tourists, from the United States, Switzerland and the Netherlands, were killed in the Central Asian country on Sunday, the authorities said. "We are considering all possibilities", said Ramazon Rakhimov, the interior minister, according to AFP news agency.

Rakhimzoda said one suspect was killed while resisting arrest, his ministry said two suspects were killed and the U.S. Embassy reported three. Three more are still at large.

An indistinct video of the murders shows a dark vehicle turning on a country road, apparently after a crash that had knocked some cyclists to the ground. "The victim's condition is stable", said Rahimzoda, without mentioning a nationality.

The Government of Tajik President Imomali Rakhmon - who expressed condolences to the US, Swiss and Dutch authorities on Monday - fought Islamist guerrillas in a 1992-1997 civil war that claimed tens of thousands of lives.

Four suspects have been detained, according to the Interior Ministry.

The Islamic State jihadist group had on Monday claimed the attack on a group of seven tourists cycling in the Danghara district, about 100 kilometres from Tajikistan's capital Dushanbe.

Swiss Foreign Ministry spokeswoman Silvia Mueller said that Swiss authorities are in contact with Tajik officials and that while the circumstances of the incident are still unclear, the Swiss government's travel advice for Tajikistan notes the risk of attacks and the bad road traffic situation in the country.

The group said it carried out an attack on "citizens of the crusader coalition", but didn't provide any further evidence of its involvement. Last year, Asia-Plus reported that over a thousand Tajik citizens have been fighting in the ranks of Islamic State.