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Islamic State (IS) militants killed about 100 people in a series of attacks on government-held parts of southwestern Syria on Wednesday, including multiple suicide blasts in Sweida city, the jihadist group and official sources said.

In the northeastern Hasakeh province, an IED in Al Shaddadi city killed one and damaged a auto.

The Syrian Observatory for Human Rights said the attacks killed 32 people, including civilians and fighters, in the city and its countryside.

Syrian civil defence volunteers, known as the White Helmets, move a victim from the site of an airstrike in the al-Sakhour neighborhood of the rebel-held part of eastern Aleppo, Syria, on September 21, 2016. At least 45 militants died carrying it out, the Observatory said.

President Bashar al-Assad's forces are now fighting to capture the last-remaining rebel villages in the southern part of the Golan Heights.

News websites in Sweida alleged that some of the jihadists who took part in Wednesday's attack had been given safe passage out of Yarmuk.

However, Israel said it will continue to escalate attacks along its frontier and elsewhere in Syria where it suspects Iranian-backed forces are stationed.

The city of Deraa was the cradle of the uprising against President Bashar al-Assad more than seven years ago.

It comes days after a Syrian fighter jet was shot down by Israeli forces claiming it had entered their airspace.

Fierce clashes between the two sides have killed 49 regime fighters and 67 jihadists.

They then moved on to Quneitra, the neighbouring province which borders the Israeli-annexed Golan Heights.

A senior member of the Syrian "White Helmet" rescue workers called on Thursday for the United Nations to save his colleagues trapped in the southwest by advancing government forces.

The Russian military said that IS attempted to bring Israel into conflict with the Syrian regime army by firing across the border.

Earlier this month, Israeli Prime Minister Binyamin Netanyahu visited Moscow for talks with Syrian regime backer Vladimir Putin about Damascus and Tehran.

More than 350,000 people have been killed and millions displaced since Syria's war started in 2011 with the brutal repression of anti-government protests. The group also has a small presence on the eastern edge of Sweida province. The others were killed in suicide attacks in the provincial capital.

After air raid sirens sounded in the south of the Israeli-occupied Golan Heights, the army said rockets had been fired from Syria towards Israel.