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Pompeo's fate is still not entirely certain with the Senate Foreign Relations Committee set to consider his nomination Monday afternoon. 'The Dems will not approve hundreds of good people, including the Ambassador to Germany.

After the Senate considers Pompeo's nomination, two other Trump nominees could have tough confirmation battles: Gina Haspel to be the next Central Intelligence Agency director and Ronny L. Jackson to be the next head of the Department of Veterans Affairs.

"We are in an era where somebody like this, who is qualified, unfortunately, is likely to be voted out without recommendation or with a negative recommendation", Corker said Sunday on "State of the Union" on CNN. "The left, the base on the Democratic side abhors the president and I realize many of them just don't want to do anything that shows a proxy of support for Trump by voting for his secretary of state", Corker said. A full Senate vote is expected to be very close. Despite the snub, the full Senate is expected to approve CIA Director Pompeo's nomination later this week thanks to a handful of Democratic votes.

The Foreign Relations panel was due to vote later on Monday on Pompeo, and he could become the first secretary of state nominee not to win the panel's support. Rand Paul of Kentucky remains opposed, despite personal overtures from the president.

Democratic Sen. Joe Manchin tweeted that he will support Pompeo in his confirmation vote, increasing his chances of being confirmed by the chamber. Dianne Feinstein of California, Tim Kaine of Virginia, Brian Schatz of Hawaii and Jeanne Shaheen of New Hampshire.

Both Short and Sanders pointed to widespread support from Republicans for President Barack Obama's nominations of Hillary Clinton and John F. Kerry as secretary of state during the Democrat's tenure.

White House press secretary Sarah Huckabee Sanders on Monday urged Democrats to give the green light to Pompeo.

'I do not make this decision lightly or without reservations, ' Coons said in a statement Friday.

Mike Pompeo spent his Easter working in a tense diplomatic environment to prevent a nuclear crisis on the Korean Peninsula from spiraling out of control. Senate Majority Leader Mitch McConnell, R-Ky., still intends to hold a full Senate confirmation vote this week, but the absence of an affirmative committee vote is unprecedented for a State nominee, according to the Senate Historical Office.

The chairman of the committee, Republican Senator Bob Corker, set up the Trump comparison of the vote last week on the Senate floor. But Democrats have assailed Pompeo for a record of bellicose statements which they say are at odds with his prospective job as the top United States diplomat, and also have cited anti-Muslim and anti-LGBTQ statements he has made in the past.