Davina McCall, guest announcer Stephen Merchant and regular segment presenters Stephen Mulhern and Scarlett Moffatt all offered support during the show - but Dec was the official solo host. "Good luck, Dec. Tough night but we're all rooting for you mate". He will reportedly feature in tonight's programme as part of a pre-recorded Saturday Knight Takeaway sketch.
Ant sought treatment last week after he was arrested on suspicion of drink-driving in Putney, South West London.
Donnelly who recently confirmed he is going to be a father, will also present next week's final episode in Florida alone.
He will appear in court on April 4. Finally, the show's producers may opt to avoid mentioning Ant's absence entirely.
"They want to be respectful... while not bringing down the mood of the show".
"Takeaway is all about having fun and they fear a sombre start may seriously effect the quality of the output".
"I've got twice the amount of work to do, so we're going to crack on", Dec said, before moving on quickly to explain what tonight's show has in store.
An insider explained: "It's going to be a odd feeling fronting the show on his own".
He was right. Dec did do a remarkably good job of holding the format together for its 90-minute broadcast.
The show - which was cancelled last Saturday - was labelled a success as Dec oversaw an nearly seamless live 90-minute show with his only mishap dropping a carton of popcorn.
"We made a promise to take hundreds of deserving winners to Florida to watch the series finale, and we will honour that".