On Thursday, 24 civilians were killed in air strikes and rocket fire on Eastern Ghouta, the Britain-based Syrian Observatory for Human Rights monitor said.
Rebels, who accuse the government of "scorched earth" tactics, said they were deploying more guerrilla-style ambushes in lost territory, trying to stop further advances.
Medical facilities supported by Doctors Without Borders (MSF) have received over 1,000 dead and 4,800 wounded in Syria's rebel-held Eastern Ghouta in just two weeks, the organization said in a statement.
"5.8 million Syrians are on the move, whether externally or internally. and half of this is children, so children are affected most", Fore said.
It is believed that about 400,000 people still live in the besieged area, which suffers from acute food and medicine shortages.
That brought the toll in more than two weeks of bombing to 810 civilians, including 179 children. The area has already been under government siege fore months increasing the suffering of residents.
Twenty-eight civilians were killed Wednesday by Syrian Government airstrikes in besieged Eastern Ghouta, according to rebels' civil defense agency.
Over those years, and in addition to ongoing attacks using conventional weapons, the area has witnessed multiple chemical weapons attacks that the Syrian government and Russian Federation persistently frame as being orchestrated by rebel groups, when all evidence emerging from the ground points the finger at the government and its allies.
Meanwhile, the agency said a U.S. spy airplane earlier conducted a reconnaissance operation over the Russian military bases in Syria.
Russian Federation has offered rebels and their families safe passage out of Eastern Ghouta, promising to protect insurgents from prosecution, Russia's Defense Ministry said Tuesday in a Facebook post.
Sedky added that "the situation is evolving rapidly on the ground, which doesn't allow us to carry out the operation in such conditions".
Syrians children receive treatment for breathing difficulties at a clinic in Syria's Eastern Ghouta.
"A convoy of UN agencies, the Syrian Arab Red Crescent, and an worldwide Red Cross committee, who were providing vital humanitarian aids to 27,500 needy people in Douma, in east Ghouta, were unable to do so because of insecurity", said the spokesperson for the UN Secretary General.
The government firmly denies this.
"The entire city of Jandairis was liberated from the secessionist gangs", said the commander, who goes by the name Abu Saleh.